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1

Collagen receptors integrin alpha2beta1 and discoidin domain receptor 1 regulate maturation of the glomerular basement membrane and loss of integrin alpha2beta1 delays kidney fibrosis in COL4A3 knockout mice

Rubel, Diana, Frese, Jenny, Martin, Maria, Leibnitz, Alexander, Girgert, Rainer, Miosge, Nicolai, Eckes, Beate, Müller, Gerhard-Anton, Gross, Oliver

Journal:

Year:

2014

Language:

english

File:

PDF, 2.10 MB

english, 2014

2

New developments on skin fibrosis - Essential signals emanating from the extracellular matrix for the control of myofibroblasts

Schulz, Jan-Niklas, Plomann, Markus, Sengle, Gerhard, Gullberg, Donald, Krieg, Thomas, Eckes, Beate

Journal:

Year:

2018

Language:

english

File:

PDF, 1.01 MB

english, 2018

3

A compound heterozygote patient with Ehlers-Danlos syndrome type VI has a deletion in one allele and a splicing defect in the other allele of the lysyl hydroxylase gene

Birgitta Pousi, Timo Hautala, James C. Hyland, Jukka Schröter, Beate Eckes, Kari I. Kivirikko, Raili Myllylä

Journal:

Year:

1998

Language:

english

File:

PDF, 229 KB

english, 1998

4

High expression and autoinduction of monocyte chemoattractant protein-1 in scleroderma fibroblasts

Toshiyuki Yamamoto, Beate Eckes, Thomas Krieg

Journal:

European Journal of Immunology

Year:

2001

Language:

english

File:

PDF, 101 KB

english, 2001

5

α-melanocyte–stimulating hormone suppresses bleomycin-induced collagen synthesis and reduces tissue fibrosis in a mouse model of scleroderma: Melanocortin peptides as a novel treatment strategy for scleroderma?

Agatha Kokot, Anca Sindrilaru, Meinhard Schiller, Cord Sunderkötter, Claus Kerkhoff, Beate Eckes, Karin Scharffetter-Kochanek, Thomas A. Luger, Markus Böhm

Journal:

Arthritis & Rheumatism

Year:

2009

Language:

english

File:

PDF, 778 KB

english, 2009

6

In vitro reconstituted skin as a tool for biology, pharmacology and therapy: a review

Beate Eckes, Thomas Krieg, Betty V. Nusgens, Charles M. Lapière

Journal:

Wound Repair and Regeneration

Year:

1995

Language:

english

File:

PDF, 1.38 MB

english, 1995

7

Kinetic Targeting of pegylated liposomal Doxorubicin: a new Approach to Reduce Toxicity during Chemotherapy (CARL-trial)

Jürgen Eckes, Oliver Schmah, Jan W Siebers, Ursula Groh, Stefan Zschiedrich, Beate Rautenberg, Annette Hasenburg, Martin Jansen, Martin J Hug, Karl Winkler, Gerhard Pütz

Journal:

Year:

2011

Language:

english

File:

PDF, 282 KB

english, 2011

8

Cell-matrix interactions in dermal repair and scarring

Beate Eckes, Roswitha Nischt, Thomas Krieg

Journal:

Fibrogenesis & Tissue Repair

Year:

2010

Language:

english

File:

PDF, 691 KB

english, 2010

9

Integrin α2-deficient mice provide insights into specific functions of collagen receptors in the kidney

Rainer Girgert, Maria Martin, Jenny Kruegel, Nicolai Miosge, Johanna Temme, Beate Eckes, Gerhard-Anton Müller, Oliver Gross

Journal:

Fibrogenesis & Tissue Repair

Year:

2010

Language:

english

File:

PDF, 5.87 MB

english, 2010

10

Interactions of fibroblasts with the extracellular matrix: implications for the understanding of fibrosis

Beate Eckes, Daniela Kessler, Monique Aumailley, Thomas Krieg

Journal:

Springer Seminars in Immunopathology

Year:

2000

Language:

english

File:

PDF, 1.06 MB

english, 2000

11

Pathogenesis of fibrosis: type 1 collagen and the skin

Maria Trojanowska, E. Carwile LeRoy, Beate Eckes, Thomas Krieg

Journal:

Journal of Molecular Medicine

Year:

1998

Language:

english

File:

PDF, 217 KB

english, 1998

12

Interactions of fibroblasts with the extracellular matrix: implications for the understanding of fibrosis

Beate Eckes, Daniela Kessler, Monique Aumailley, Thomas Krieg

Journal:

Seminars in Immunopathology

Year:

2000

Language:

english

File:

PDF, 1.06 MB

english, 2000

13

Integrin α2β1 deficiency does not affect contact hypersensitivity

Manon C. Zweers, Lisa Siewe, Claudia Wickenhauser, Thomas Krieg, Axel Roers, Beate Eckes

Journal:

Archives of Dermatological Research

Year:

2006

Language:

english

File:

PDF, 353 KB

english, 2006

14

Scleroderma - news to tell

Beate Eckes, Nicolas Hunzelmann, Pia Moinzadeh, Thomas Krieg

Journal:

Archives of Dermatological Research

Year:

2007

Language:

english

File:

PDF, 241 KB

english, 2007

15

Bleomycin increases steady-state levels of type I collagen, fibronectin and decorin mRNAs in human skin fibroblasts

T. Yamamoto, Beate Eckes, Thomas Krieg

Journal:

Archives of Dermatological Research

Year:

2000

Language:

english

File:

PDF, 132 KB

english, 2000

16

New developments in fibroblast and myofibroblast biology: Implications for fibrosis and scleroderma

David J. Abraham, Beate Eckes, Vineeth Rajkumar, Thomas Krieg

Journal:

Current Rheumatology Reports

Year:

2007

Language:

english

File:

PDF, 758 KB

english, 2007

17

Expression of Type VI Collagen mRNA During Wound Healing.

Oono, Takashi, Specks, Ulrich, Eckes, Beate, Majewski, Slawomir, Hunzelmann, Nicolas, Timpl, Rupert, Krieg, Thomas

Journal:

The Journal of Investigative Dermatology

Year:

1993

File:

PDF, 3.41 MB

1993

18

TGFbeta-1 and TNFalpha Expression in the Epidermis of Patients with Epidermodysplasia Verruciformis.

Majewski, Slawomir, Hunzelmann, Nicolas, Nischt, Roswitha, Eckes, Beate, Rudnicka, Lidia, Orth, Gerard, Krieg, Thomas, Jablonska, Stefania

Journal:

The Journal of Investigative Dermatology

Year:

1991

File:

PDF, 2.91 MB

1991

19

High plasminogen activator inhibitor type 2 expression is a hallmark of scleroderma fibroblasts in vitro

Daniela Kessler-Becker, Sigrun Smola, Thomas Krieg, Beate Eckes

Journal:

Experimental Dermatology

Year:

2004

Language:

english

File:

PDF, 1.41 MB

english, 2004

20

Altered regulation of collagen metabolism in scleroderma fibroblasts grown within three-dimensional collagen gels

Cornelia Mauch, Ewa Kozlowska, Beate Eckes, Thomas Krieg

Journal:

Experimental Dermatology

Year:

1992

Language:

english

File:

PDF, 5.56 MB

english, 1992

21

Decreased expression of α2β1 integrin in scleroderma fibroblasts

Ewa Kozlowska, Stephan Sollberg, Cornelia Mauch, Beate Eckes, C. Eberhard Klein, Thomas Krieg

Journal:

Experimental Dermatology

Year:

1996

Language:

english

File:

PDF, 6.24 MB

english, 1996

22

Signalling and regulation of collagen I synthesis by ET-1 and TGF-β1

Angelika Horstmeyer, Christoph Licht, Gabriele Scherr, Beate Eckes, Thomas Krieg

Journal:

Year:

2005

Language:

english

File:

PDF, 333 KB

english, 2005

23

Integrin α2β1 Is Required for Regulation of Murine Wound Angiogenesis but Is Dispensable for Reepithelialization

Zweers, Manon C, Davidson, Jeffrey M, Pozzi, Ambra, Hallinger, Ralf, Janz, Katharina, Quondamatteo, Fabio, Leutgeb, Barbara, Krieg, Thomas, Eckes, Beate

Journal:

The Journal of Investigative Dermatology

Year:

2006

Language:

english

File:

PDF, 552 KB

english, 2006

24

Mechanical Tension and Integrin α2β1 Regulate Fibroblast Functions

Eckes, Beate, Zweers, Manon C, Zhang, Zhi Gang, Hallinger, Ralf, Mauch, Cornelia, Aumailley, Monique, Krieg, Thomas

Journal:

JID Symposium Proceedings

Year:

2006

Language:

english

File:

PDF, 146 KB

english, 2006

25

The loss of α2β1 integrin suppresses joint inflammation and cartilage destruction in mouse models of rheumatoid arthritis

Marvin A. Peters, Doreen Wendholt, Simon Strietholt, Svetlana Frank, Noreen Pundt, Adelheid Korb-Pap, Leo A. B. Joosten, Wim B. van den Berg, George Kollias, Beate Eckes, Thomas Pap

Journal:

Arthritis & Rheumatism

Year:

2012

Language:

english

File:

PDF, 254 KB

english, 2012

26

Surface morphology and mechanical properties of fibroblasts from scleroderma patients

Adam Reich, Michael Meurer, Beate Eckes, Jens Friedrichs, Daniel J. Muller

Journal:

Journal of Cellular and Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 1.27 MB

english, 2009

27

Apoptosis in v-myc-transfected MSU-1.1 fibroblasts is induced by cell-matrix contact and differs from that of normal dermal fibroblasts

Stephan Niland, Anja Cremer, Katja Herzhoff, Betty V. Nusgens, Charles M. Lapière, Thomas Krieg, Beate Eckes

Journal:

In Vitro Cellular & Developmental Biology - Animal

Year:

2001

Language:

english

File:

PDF, 1.62 MB

english, 2001

28

Comparison of Columnar Water-Vapor Measurements from Solar Transmittance Methods

Schmid, Beat, Michalsky, Joseph J., Slater, Donald W., Barnard, James C., Halthore, Rangasayi N., Liljegren, James C., Holben, Brent N., Eck, Thomas F., Livingston, John M., Russell, Philip B.

Journal:

Year:

2001

Language:

english

File:

PDF, 1.13 MB

english, 2001

29

Effect of Interleukin-10 on the Gene Expression of Type I Collagen, Fibronectin, and Decorin in Human Skin Fibroblasts: Differential Regulation by Transforming Growth Factor-β and Monocyte Chemoattractant Protein-1

Toshiyuki Yamamoto, Beate Eckes, Thomas Krieg

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 183 KB

english, 2001

30

Cell–Matrix Interactions Induce Tyrosine Phosphorylation of MAP Kinases ERK1 and ERK2 and PLCγ-1 in Two-Dimensional and Three-Dimensional Cultures of Human Fibroblasts

Oliver Langholz, Dagmar Roeckel, Dirk Petersohn, Eva Broermann, Beate Eckes, Thomas Krieg

Journal:

Experimental Cell Research

Year:

1997

Language:

english

File:

PDF, 309 KB

english, 1997

31

Interleukin-6 expression by fibroblasts grown in three-dimensional gel cultures

Beate Eckes, Nicolas Hunzelmann, H.-W.Löms Ziegler-Heitbrock, Agatha Urbanski, Thomas Luger, Thomas Krieg, Cornelia Mauch

Journal:

Year:

1992

Language:

english

File:

PDF, 497 KB

english, 1992

32

Downregulation of collagen synthesis in fibroblasts within three-dimensional collagen lattices involves transcriptional and posttranscriptional mechanisms

Beate Eckes, Cornelia Mauch, Gabriele Hüppe, Thomas Krieg

Journal:

Year:

1993

Language:

english

File:

PDF, 533 KB

english, 1993

33

Biofunctionalization of a generic collagenous triple helix with the α2β1 integrin binding site allows molecular force measurements

Stephan Niland, Christoph Westerhausen, Stefan W. Schneider, Beate Eckes, Matthias F. Schneider, Johannes A. Eble

Journal:

The International Journal of Biochemistry & Cell Biology

Year:

2011

Language:

english

File:

PDF, 1.60 MB

english, 2011

34

Endorepellin evokes SHP1 activity in endothelial cells

Alexander Nystrom, Zabeena P. Shaik, Ambra Pozzi, Thomas Krieg, Beate Eckes, Renato V. Iozzo

Journal:

Year:

2008

Language:

english

File:

PDF, 79 KB

english, 2008

35

Identification of novel interaction partners for the conserved membrane proximal region of α-integrin cytoplasmic domains

Viktor Wixler, Emmanuel Laplantine, Dirk Geerts, Arnoud Sonnenberg, Dirk Petersohn, Beate Eckes, Mats Paulsson, Monique Aumailley

Journal:

Year:

1999

Language:

english

File:

PDF, 107 KB

english, 1999

36

Transforming growth factor-β reverses deficient expression of type (I) collagen in cultured fibroblasts of a patient with metageria

Nicolas Hunzelmann, Uwe Ueberham, Beate Eckes, Konrad Herrmann, Thomas Krieg

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

1997

Language:

english

File:

PDF, 704 KB

english, 1997

37

Fibroblast-matrix interactions in wound healing and fibrosis

Beate Eckes, Paola Zigrino, Daniela Kessler, Olaf Holtkötter, Pierre Shephard, Cornelia Mauch, Thomas Krieg

Journal:

Year:

2000

Language:

english

File:

PDF, 194 KB

english, 2000

38

Cyclic mechanical stress downregulates endothelin-1 and its responsive genes independently of TGFβ1 in dermal fibroblasts

Andreas S. Peters, Georg Brunner, Katrin Blumbach, David J. Abraham, Thomas Krieg, Beate Eckes

Journal:

Experimental Dermatology

Year:

2012

Language:

english

File:

PDF, 505 KB

english, 2012

39

Regulation of the Atheroma-Enriched Protein, SPRR3, in Vascular Smooth Muscle Cells through Cyclic Strain is Dependent on Integrin α1β1/Collagen Interaction

Amy L. Pyle, James B. Atkinson, Ambra Pozzi, Jeff Reese, Beate Eckes, Jeffrey M. Davidson, Dan L. Crimmins, Pampee P. Young

Journal:

The American Journal of Pathology

Year:

2008

Language:

english

File:

PDF, 2.01 MB

english, 2008

40

Native high-density lipoproteins inhibit platelet activation via scavenger receptor BI: Role of negatively charged phospholipids

Martin F. Brodde, Suzanne J.A. Korporaal, Grazyna Herminghaus, Manfred Fobker, Theo J.C. Van Berkel, Uwe J.F. Tietge, Horst Robenek, Miranda Van Eck, Beate E. Kehrel, Jerzy-Roch Nofer

Journal:

Atherosclerosis

Year:

2011

Language:

english

File:

PDF, 451 KB

english, 2011

41

Role of stem cell factor and monocyte chemoattractant protein-1 in the interaction between fibroblasts and mast cells in fibrosis

Yamamoto, Toshiyuki, Hartmann, Karin, Eckes, Beate, Krieg, Thomas

Journal:

Journal of Dermatological Science

Year:

2001

Language:

english

File:

PDF, 159 KB

english, 2001

42

Expression of monocyte chemoattractant protein-1 in the lesional skin of systemic sclerosis

Yamamoto, Toshiyuki, Eckes, Beate, Hartmann, Karin, Krieg, Thomas

Journal:

Journal of Dermatological Science

Year:

2001

Language:

english

File:

PDF, 510 KB

english, 2001

43

Functional characterization of mesenchymal precursor cells from bone marrow

Wallmichrath, Ansgar, Eckes, Beate, Schmitz, Beate, Krieg, Thomas

Journal:

Journal of Dermatological Science

Year:

1998

Language:

english

File:

PDF, 149 KB

english, 1998

44

Replacement of human primary dermal fibroblasts in in vitro toxico pharmacological models by immortalized cell lines

Herzhoff, Katja, Maniglia, Salvatore, Eckes, Beate, Nusgens, Betty, Krieg, Thomas, Lapière, Charles

Journal:

Journal of Dermatological Science

Year:

1998

Language:

english

File:

PDF, 190 KB

english, 1998

45

Gene regulation by mechanical forces in human dermal fibroblasts

Dethlefsen, Silke, Eckes, Beate, Krieg, Thomas

Journal:

Journal of Dermatological Science

Year:

1998

Language:

english

File:

PDF, 190 KB

english, 1998

46

Regulation of collagen and collagenase gene expression in human fibroblasts by monocyte chemoattractant protein-1 (MCP-1)

Yamamoto, Toshiyuki, Hartmann, Karin, Eckes, Beate, Krieg, Thomas

Journal:

Journal of Dermatological Science

Year:

1998

Language:

english

File:

PDF, 183 KB

english, 1998

47

Expression of TGF-β1, -β2 and -β3 in localized and systemic scleroderma

Querfeld, Christiane, Eckes, Beate, Huerkamp, Christina, Krieg, Thomas, Sollberg, Stephan

Journal:

Journal of Dermatological Science

Year:

1999

Language:

english

File:

PDF, 1.40 MB

english, 1999

48

Stabilization of integrin-linked kinase by the Hsp90-CHIP axis impacts cellular force generation, migration and the fibrotic response

Radovanac, Korana, Morgner, Jessica, Schulz, Jan-Niklas, Blumbach, Katrin, Patterson, Cam, Geiger, Tamar, Mann, Matthias, Krieg, Thomas, Eckes, Beate, Fässler, Reinhard, Wickström, Sara A

Journal:

The EMBO Journal

Year:

2013

Language:

english

File:

PDF, 3.40 MB

english, 2013

49

CD49b-dependent establishment of T helper cell memory

Hanazawa, Asami, Hayashizaki, Koji, Shinoda, Kenta, Yagita, Hideo, Okumura, Ko, Löhning, Max, Hara, Takahiro, Tani-ichi, Shizue, Ikuta, Koichi, Eckes, Beate, Radbruch, Andreas, Tokoyoda, Koji, Nakayam

Journal:

Immunology & Cell Biology

Year:

2013

Language:

english

File:

PDF, 1.60 MB

english, 2013

50

Tropisetron suppresses collagen synthesis in skin fibroblasts via α7 nicotinic acetylcholine receptor and attenuates fibrosis in a scleroderma mouse model

Stegemann, Agatha, Sindrilaru, Anca, Eckes, Beate, del Rey, Adriana, Heinick, Alexander, Schulte, Jan S., Müller, Frank U., Grando, Sergei A., Fiebich, Bernd L., Scharffetter-Kochanek, Karin, Luger, T

Journal:

Arthritis & Rheumatism

Year:

2013

Language:

english

File:

PDF, 917 KB

english, 2013

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